Axel Benner Selected Research

midostaurin

1/2022	Genomic landscape of patients with FLT3-mutated acute myeloid leukemia (AML) treated within the CALGB 10603/RATIFY trial.
1/2022	Midostaurin plus intensive chemotherapy for younger and older patients with AML and FLT3 internal tandem duplications.
1/2019	Midostaurin added to chemotherapy and continued single-agent maintenance therapy in acute myeloid leukemia with FLT3-ITD.

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Axel Benner Research Topics

Disease

69	Neoplasms (Cancer) 01/2024 - 01/2003
24	Multiple Myeloma 12/2024 - 11/2002
24	Colorectal Neoplasms (Colorectal Cancer) 11/2023 - 09/2003
20	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 10/2023 - 02/2004
13	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 01/2022 - 08/2002
13	Neoplasm Metastasis (Metastasis) 11/2018 - 01/2004
11	Breast Neoplasms (Breast Cancer) 02/2024 - 11/2003
9	Melanoma (Melanoma, Malignant) 01/2018 - 02/2002
9	Neuroblastoma 01/2016 - 01/2006
8	Immunoglobulin Light-chain Amyloidosis 10/2021 - 03/2014
8	Medulloblastoma 04/2012 - 05/2004
7	Leukemia 01/2024 - 05/2008
7	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2023 - 06/2003
6	Hematologic Neoplasms (Hematological Malignancy) 03/2024 - 04/2013
6	Amyloidosis 01/2021 - 05/2008
6	Chromosome Aberrations (Chromosome Abnormalities) 01/2016 - 05/2008
5	Colonic Neoplasms (Colon Cancer) 11/2023 - 09/2005
5	Infections 07/2023 - 01/2007
5	Carcinogenesis 01/2020 - 11/2003
4	Prostatic Neoplasms (Prostate Cancer) 05/2024 - 01/2022
4	Ependymoma 11/2012 - 04/2006
4	Carcinoma (Carcinomatosis) 10/2012 - 01/2004
4	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2009 - 10/2003
4	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 01/2009 - 10/2004
3	Sepsis (Septicemia) 02/2024 - 01/2008
3	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2024 - 10/2015
3	Lymphoma (Lymphomas) 01/2024 - 12/2006
3	Pancreatic Neoplasms (Pancreatic Cancer) 08/2023 - 01/2016
3	Pathologic Complete Response 07/2023 - 04/2006
3	Paraproteinemias (Monoclonal Gammopathy) 01/2023 - 05/2008
3	Lung Neoplasms (Lung Cancer) 04/2022 - 12/2015
3	Inflammation (Inflammations) 04/2022 - 11/2007
3	Renal Insufficiency (Renal Failure) 01/2019 - 11/2006
3	Brain Neoplasms (Brain Tumor) 03/2009 - 11/2007
3	Non-Hodgkin Lymphoma (Lymphosarcoma) 01/2009 - 10/2004
2	Thrombotic Microangiopathies 03/2024 - 09/2017
2	Colitis 02/2024 - 11/2007
2	Pneumonia (Pneumonitis) 02/2024 - 07/2023
2	Residual Neoplasm 09/2023 - 09/2004
2	Thrombocytopenia (Thrombopenia) 07/2023 - 10/2004
2	Febrile Neutropenia 07/2023 - 07/2021
2	Genomic Instability 01/2022 - 01/2021
2	Chromothripsis 01/2022 - 01/2017

Drug/Important Bio-Agent (IBA)

29	Proteins (Proteins, Gene)FDA Link 01/2023 - 11/2003
20	Biomarkers (Surrogate Marker)IBA 04/2022 - 11/2002
15	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 01/2004
12	Dexamethasone (Maxidex)FDA LinkGeneric 02/2024 - 07/2010
12	Messenger RNA (mRNA)IBA 01/2016 - 11/2003
8	Melphalan (Alkeran)FDA LinkGeneric 01/2021 - 11/2006
8	MicroRNAs (MicroRNA)IBA 01/2017 - 12/2011
7	Rituximab (Mabthera)FDA Link 01/2022 - 10/2004
6	Lenalidomide (CC 5013)FDA Link 02/2024 - 01/2017
6	Phosphotransferases (Kinase)IBA 01/2022 - 01/2004
5	RNA (Ribonucleic Acid)IBA 02/2024 - 11/2003
5	Peptides (Polypeptides)IBA 01/2020 - 04/2008
5	Tretinoin (Retinoic Acid)FDA LinkGeneric 12/2016 - 01/2009
4	Immunoglobulins (Immunoglobulin)IBA 12/2024 - 08/2002
4	ProBaseIBA 05/2024 - 01/2022
4	Bortezomib (Velcade)FDA Link 02/2024 - 04/2015
4	fludarabineIBA 07/2023 - 10/2004
4	Gemtuzumab (Mylotarg)FDA Link 07/2023 - 01/2016
4	Immunoglobulin Heavy Chains (Immunoglobulin Heavy Chain)IBA 01/2022 - 02/2006
4	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2022 - 10/2004
4	SteroidsIBA 11/2020 - 08/2011
4	3' Untranslated Regions (3' UTR)IBA 11/2018 - 09/2005
4	CytokinesIBA 01/2018 - 12/2011
4	AntigensIBA 01/2018 - 02/2015
4	Complementary DNA (cDNA)IBA 08/2007 - 08/2004
3	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2023 - 06/2016
3	Genetic Markers (Genetic Marker)IBA 10/2023 - 01/2017
3	Cytarabine (Cytosar-U)FDA LinkGeneric 10/2023 - 01/2016
3	VaccinesIBA 01/2023 - 01/2018
3	midostaurinIBA 01/2022 - 01/2019
3	Calcibiotic Root Canal SealerIBA 10/2021 - 07/2007
3	ParaffinIBA 10/2021 - 01/2012
3	Granulocyte Colony-Stimulating Factor (G-CSF)IBA 07/2021 - 06/2007
3	Core Binding Factors (Core-Binding Factor)IBA 12/2020 - 01/2017
3	Blood Proteins (Serum Proteins)IBA 01/2020 - 05/2015
3	Fluorouracil (Carac)FDA LinkGeneric 07/2018 - 12/2015
3	Proto-Oncogene Proteins B-rafIBA 10/2005 - 01/2004
3	Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA 10/2005 - 01/2004
2	Prostate-Specific Antigen (Semenogelase)IBA 05/2024 - 10/2023
2	Monoclonal AntibodiesIBA 02/2024 - 07/2005
2	carfilzomibIBA 09/2023 - 01/2022
2	isatuximabIBA 09/2023 - 01/2022
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2023 - 11/2016
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 01/2022 - 05/2008
2	Formaldehyde (Formol)FDA Link 10/2021 - 01/2012
2	daratumumabIBA 01/2021 - 01/2020
2	AntibodiesIBA 01/2021 - 01/2018

Therapy/Procedure

41	Therapeutics 02/2024 - 11/2003
26	Drug Therapy (Chemotherapy) 11/2023 - 05/2004
21	Stem Cell Transplantation 03/2024 - 06/2003
8	Transplantation 03/2024 - 09/2004
5	Radiotherapy 03/2016 - 11/2003
3	Adjuvant Chemotherapy 01/2022 - 09/2005
3	Immunotherapy 01/2021 - 02/2002
3	Salvage Therapy 01/2020 - 07/2013
3	Autologous Transplantation 01/2016 - 09/2004
2	Cell Transplantation 01/2022 - 01/2016